The Indian Rheumatology Association

The Professional Organization of Rheumatologists and other Health Professionals in India

Research From India

Summary of published articles from India
Edited by: Dr. Avinash Jain , Dr. Padmanabha Shenoy

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Compiled By
DNB DM (Rheumatology)
APLAR Clinical and Research Fellow(Myositis) at the Aintree University hospital

Research from India

October – January 2018

Inflammatory Arthritides

Research in inflammatory arthritides in the past three months has covered a wide spectrum of areas involving basic pathogenesis, clinical aspects, therapeutic questions and epidemiology. However clinical aspects have been the major focus.

In understanding the pathogenic mechanisms in rheumatoid arthritis, Michael BR et al1 found higher levels of microparticles (MPs), platelet derived MPs and MPs other than those of platelet origin in the synovial fluid as well as peripheral blood hence suggesting their role in the pathogenesis of the disease. Also higher levels of platelet derived MPs may suggest their role in systemic involvement. Furthermore, increased levels of MPs other than those of platelet origin indicate the necessity to study the MPs from other cell lineages.

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